Background: Quality indicators are one of the methodologies to improve the quality of hospital services. The patients admitted in hospital to which catheters are applied as a part of treatment are more likely to suffer with urinary tract infections (UTI). Objectives: To determine the effectiveness of application of quality indicator in reduction of cases of UTI and preventing CAUTI and bacteriuria of catheterized patients. Material and Methods: This study was conducted on patients requiring catheterization as a part of treatment. The intervention included pre-test, lecture and demonstration, training of proper insertion, maintenance and removal of catheter and post-test. The results of pre and post intervention were compared. Results: The present study included 1645 patients with catheterization from different sections of the hospital. The required data collected including 878 patients before intervention and 767 patients after intervention deemed second part of the study. Clinically suspected patients of UTI among catheterized patients were 80 with 8 culture confirmation of infection and 2 of them with multidrug resistant isolates. In second part of study, there were 28 patients suspected with infection with 4 culture positives. Conclusion: A significant improvement was observed after the application of QI. It is recommended to apply such indicators not only of urinary tract infections but different types of services in hospital to benefit both hospital and patient. Application of QI in different medical services is beneficial to improve various health services.